Uniform bead dosing from a stable dispersion

Details Uniform bead dosing from a stable dispersion Uniform bead dosing from a stable dispersion

2006-07-25

2006-07-25

Housel, James (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

C436S518000, C436S173000, C424S009362, C424S001290, C424S602000, C128S126100, C128S126100, C514S492000, C423S263000, C423S301000, C423S305000, C252S391000, C252S391000, C044S361000

Reexamination Certificate

active

07081366

ABSTRACT:
A primary antibody bead suspension for an enzyme-linked immunoassay (“ELISA”) procedure is formed of a quantity of primary antibody coated magnetic beads (3) uniformly dispersed and held in suspension (9) by a thixotropic non-Newtonian fluid (1). To remove the thixotropic non-Newtonian fluid prior to application in the ELISA procedure, a magnet (12) is placed against the side of the non-magnetic vessel (9) holding the suspension to draw the magnetic beads against the side while the thixotropic fluid is washed away by pumping (14,16,15&17) and replaced by a saline buffer solution.

REFERENCES:
patent: 3985649 (1976-10-01), Eddelman
patent: 4430251 (1984-02-01), Patterson et al.
patent: 5344640 (1994-09-01), Deutsch et al.
patent: 5429836 (1995-07-01), Fuisz
patent: 6815541 (2004-11-01), Usui et al.
patent: 2002/0137637 (2002-09-01), Wojtecki

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