Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-06-11
1994-09-27
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549267, 549268, 549349, A61K 31365, C07D32110
Patent
active
053507630
ABSTRACT:
Unguinol is a well-known metabolite of the fungi Aspergillus unguis and Aspergillus nidulans. Unguinol has been found to be an active growth permittant and promotant in animals, in particular, monogastric animals such as chickens. In addition, the fermentation broth also produced the additional known unguinol derivatives of folipastatin and 2-chloro unguinol as well as the novel 4-methyl derivative. All of these compounds are active animal growth permittants. Compositions containing such unguinol derivatives for use as growth permittants and promotants are also disclosed.
REFERENCES:
Sierankiewicz, et al, Acta Chemica Scandinavia 26 pp. 455-458 (1972).
Kawakara, et al, Chem Pharm Bull 36 pp. 1970-1975 (1988).
Stodula, et al, Phytochem 11, pp. 2107-2108 (1972).
Hamaro, et al, J. Antibiotics pp. 1195-1201 (1992).
Feighner Scott D.
Salituro Gino M.
Smith Jack L.
Tsou Nancy N.
DiPrima Joseph F.
Ivy C. Warren
Merck & Co. , Inc.
Rose David L.
Trinh Ba K.
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