Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1994-02-22
1997-04-08
Jones, W. Gary
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435 6, 435 9151, C12Q 168, C12P 1934
Patent
active
056187033
ABSTRACT:
Methods are provided for distinguishing between RNA and DNA templates in an amplification reaction. In a preferred embodiment of the invention, the amplification reaction is a PCR and the reaction is catalyzed by a thermostable DNA polymerase or both reverse transcription and amplification of a target RNA. The invention particularly relates to selective amplification of RNA in the presence of homologous DNA, for example, HIV nucleic acids.
REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4889818 (1989-12-01), Gelfand et al.
patent: 5035996 (1991-07-01), Hartley
Kallen et al., 1962, "The Occurrence of a ew Pyrimidine Base Replacing Thymine in a Bacteriophage DNA: 5-Hydroxymethyl Uracil" J. Mol. Biol. 5:248-250.
Karkas et al., Feb., 1972, "Action of DNA Polymerase I of Escherichia coli With DNA-RNA Hybrids as Templates" Proc. Natl. Acad. Sci. USA 69(2):398-402.
Leob et al., Mar., 1973, "Copying Natural RNAs With E. coli DNA Polymerase I" Nature New Biology 242:66-69.
Karkas Dec., 1973, "Reverse Transcription by Escherichia coli DNA Polymerase I" Proc. Natl. Acad. Sci. USA 70(12)Part II:3834-3838.
Brown, 1974, Basic Principles in Nucleic Acid Chemistry 2:41-45.
Gulati et al., Apr., 1974, "Conditions for Using DNA Polymerase I as an RNA-Dependent DNA Polymerase" Proc. Natl. Acad. Sci. USA 71(4):1035-1039.
Temin and Mizutani, The Enzymes Chapter 7, Entitled "RNA Tumor Virus DNA Polymerase," Paul Boyer, Academic Press, Inc., London, 1974 ed., pp. 211-235.
Travaglini and Leob, 1974, "Ribonucleic Acid Dependent Deoxyribonucleic Acid Synthesis by Escherichia coli Deoxyribonucleic Acid Polymerase I. Characterization of the Polymerization Reaction" Biochemistry 13(15):3010-3017.
Chien et al., 1976, "Doexyribonucleic Acid Polymerase From the Extreme Thermophile Thermus aquaticus" J. Bacteriology 127(3):1550-1557.
Houdebine, 1976, "Synthesis of DNA Complementary to the mRNAs for Milk Proteins by E. coli DNA Polymerase I" Nucleic Acids Research 3(3):615-630.
Mizutani and Temin, 1976, "Incorporation of Noncomplementary Nucleotides at High Frequencies by Ribodeoxyvirus DNA Polymerase and Escherichia coli DNA Polymerase I" Biochemistry 15:1510-1516.
Travaglini et al., 1976, "Template Recognition and Chain Elongation in DNA Synthesis in Vitro" J. Mol. Biol. 106:605-621.
Kaledin et al., 1980, "Isolation and Properties of DNA Polymerase From Extremely Thermophilic Bacterium Thermus aquaticus YT1" Biokhimiya 45(4):644-651.
"Metal Ions in Genetic Information Transfer" in Advances in Inorganic Biochemistry vol. 3, pp. 26-29, 32-35, and 42-46 published by Elsiver North Holland Inc., New York, New York, Eds. Eichom, Gunther, Louis and Marzill, Luigi, 1981.
Ruttimann et al., 1985, "DNA Polymerase From the Extremely Thermophilic Bacterium Thermus thermophilus HB-8" Eur. J. Biochem. 149:41-46.
Jones and Foulkes, 1989, "Reverse Transcription of mRNA by Thermus aquaticus DNA Polymerase" Nucleic Acids Research 17(20):8387-8388.
Kawasaki, 1989, "Amplification of RNA Sequences via Complementary DNA (cDNA)," Amplifications 3:4-6.
Lawyer et al., Apr., 1989, "Isolation, Characterization, and Expression in Escherichia coli of the DNA Polymerase Gene From Thermus aquaticus" J. Biological Chemistry 264(11):6427-6437.
Shimomaye and Salvato, 1989, "Use of Avian Myeloblastosis Virus Reverse Transcriptase at High Temperature for Sequence Analysis of Highly Structure RNA" Gene. Anal. Techn. 6:25-28.
Tabor and Richardson, 1989, "Effect of Manganese Ions on the Incorporation of Dideoxynucleotides by Bacteriophage T7 DNA Polymerase and Escherichia coli DNA Polymerase I" Proc. Natl. Acad. Sci. USA 86:4076-4080.
Mocharla et al., 1990, "Coupled Reverse Transcription-Polymerase Chain Reaction (RT-PCR) as a Sensitive and Rapid Method for Isozyme Genotyping" Gene 93:271-275.
Shaffer et al., 1990, "Amplification, Detection, and Automated Sequencing of Gibbon Interleukin-2 mRNA by Thermus aquaticus DNA Polymerase Reverse Transcription and Polymerase Chain Reaction" Analytical Biochemistry 190:292-296.
Tse and Forget, 1990, "Reverse Transcription and Direct Amplification of Cellular RNA Transcripts by Taq Polymerase" Gene 88:293-296.
Levy and Teebor, 1991, "Site Directed Substitution of 5-Hydroxymethyluracil for Thymine in Replicating Phi-X 174am3 DNA via Synthesis of 5-Hydroxymethyl-2;-Deoxyuridine-5'-Triphosphate" Nucleic Acids Research 19(12):3337-3343.
Lou et al., 1991, "Renin Gene Expression in Various Tissues Determined by Single-Step Polymerase Chain Reaction" Clinical and Experimental Pharmacology Physiology 18:357-362.
Gelfand David H.
Myers Thomas W.
Gould George M.
Hoffmann-La Roche Inc.
Jones W. Gary
Schreiber David
Sias Stacey R.
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