Unbridged bis-aryl carbinol derivatives compositions and methods

Details Unbridged bis-aryl carbinol derivatives compositions and methods Unbridged bis-aryl carbinol derivatives compositions and methods

1995-06-02

1997-09-09

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546193, 546194, A61K 31445, C07D21122, C07D21126, C07D21132

Patent

active

056657358

ABSTRACT:
Disclosed is a compound of Formula 1.0: ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein: AR.sup.1 represents ##STR2## AR.sup.2 represents ##STR3## or a five-membered heterocyclic aromatic group selected from the group consisting of Formulas I to XII, wherein the substitutable carbon atoms of the five-membered heterocyclic group can optionally be substituted with a group R.sup.1.
Also disclosed are pharmaceutical compositions containing compounds of Formula 1.0.
Further disclosed is a method for treating asthma, allergy and inflammation by administering an anti-asthmatic, anti-allergic or anti-inflammatory, respectively, effective amount of a compound of Formula 1.0.

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