Ultrasound-enhanced sampling of materials through the skin

Surgery – Truss – Pad

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

601 2, 604 22, 128760, H61B 500

Patent

active

056366329

ABSTRACT:
A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultra sound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.

REFERENCES:
patent: 3710779 (1973-01-01), Bunnell et al.
patent: 3941122 (1976-03-01), Jones
patent: 4002221 (1977-01-01), Buchalter
patent: 4372296 (1983-02-01), Fahim
patent: 4484569 (1984-11-01), Driller et al.
patent: 4692139 (1987-09-01), Stiles
patent: 4767402 (1988-08-01), Kost et al.
patent: 4780212 (1988-10-01), Kost et al.
patent: 4787888 (1988-11-01), Fox
patent: 4791915 (1988-12-01), Barsotti et al.
patent: 4804364 (1989-02-01), Dieras
patent: 4821740 (1989-04-01), Tachibana et al.
patent: 4942878 (1990-07-01), Dory
patent: 4953565 (1990-09-01), Tachibana et al.
patent: 5016615 (1991-05-01), Driller et al.
patent: 5115805 (1992-05-01), Bommannan et al.
patent: 5143063 (1992-09-01), Fellner
patent: 5158070 (1992-10-01), Dory
patent: 5231975 (1993-08-01), Bommannan et al.
Benson, H. et al., "Use of ultrasound to enhance percutaneous absorption of benzydamine" Physical Therapy (1989) 69(2):113-118.
Escoffier, C. et al., "In vitro study of the velocity of ultrasound in the skin" Bioeng. Skin (1986) 2:87-94.
Griffin, J.E. et al., "Ultrasonic movement of cortisol into pig tissue" Amer. J. Phys. Medicine (1965) 44(1):20-25.
Griffin, J.E. et al., "Physiological effects of ultrasonic energy as it is used clinically" J. Amer. Phys. Therapy Assoc. (1966) 46:18-26.
Griffin, J.E. et al., "Patients treated with ultrasonic driven hydrocortisone and with ultrasound alone" Phys. Therapy (1967) 47(7):594-601.
Griffin, J.E. et al., "Low-intensity phonophoresis of cortisol in swine" Phys. Therapy (1968) 48(12):1336-1344.
Griffin, J.E. et al., "Effect of ultrasonic frequency on phonophoresis of cortisol into swine tissues" Amer. J. Phys. Medicine (1972) 51(2):62-72.
Kost, J. et al., "Effect of therapeutic ultrasound on skin permeability" Proceed. Intern. Symp. Control. Rel. Bioact. Mater. (1989) 16(141):294-295.
Lutz, H. et al., Manual of Ultrasound: Basic Physical and Technical Principles (1984) (Berlin:Springer-Verlag) Chapter 1.
McElnay, J.E., "The influence of ultrasound on the percutaneous absorption of fluocinolone acetonide" Int. J. Pharmaceutics (1987) 40:105-110.
Miyasaki, S. et al., "External control of drug release: controlled release of insuline from a hydrophilic polymer by ultrasound irradiation in diabetic rats" J. Pharm. Pharmacol. (1988) 40:716-717.
Novak, E., "Experimental transmission of lidocaine through intact skin by ultrasound" Arch. Phys. Medicine & Rehab. (1964) 45:231-232.
Skauen, D.M. et al., "Phonophoresis" Int. J. Pharmaceutics (1984) 20:235-245.
Tyle, P. et al., "Drug delivery by phonophroesis" Pharmaceutical Research (1989) 6(5):355-361.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ultrasound-enhanced sampling of materials through the skin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ultrasound-enhanced sampling of materials through the skin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultrasound-enhanced sampling of materials through the skin will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-758535

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.