Ultrasound contrast media comprising perfluoropentane and perflu

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 95, 424673, 12866202, 12866102, 12866001, 514744, 514746, 514752, 514754, 514757, A61K 4900

Patent

active

055588549

ABSTRACT:
Ultrasound contrast media comprising gaseous perfluoropentane and gaseous perfluorohexane are disclosed.

REFERENCES:
patent: 4265251 (1981-05-01), Tickner
patent: 4276885 (1981-07-01), Tickner
patent: 4442843 (1984-04-01), Rasor et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4533254 (1985-08-01), Cooke et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4572203 (1986-02-01), Feinstein
patent: 4657756 (1987-04-01), Rasor et al.
patent: 4681119 (1987-07-01), Rasor et al.
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4718433 (1988-01-01), Feinstein
patent: 4767610 (1988-08-01), Long
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
patent: 4859363 (1989-08-01), Davis et al.
patent: 4865836 (1989-09-01), Long
patent: 4895876 (1990-01-01), Schweighardt et al.
patent: 4900540 (1990-02-01), Ryan et al.
patent: 4927623 (1990-05-01), Long
patent: 4957656 (1990-09-01), Cerny
patent: 4985550 (1991-01-01), Charpoit et al.
patent: 4987154 (1991-01-01), Long
patent: 4993415 (1991-02-01), Long
patent: 5078146 (1992-01-01), Sato
patent: 5080885 (1992-01-01), Long
patent: 5088499 (1992-02-01), Unger
patent: 5107842 (1992-04-01), Levine et al.
patent: 5114703 (1992-05-01), Wolf et al.
patent: 5123414 (1992-06-01), Unger
patent: 5137928 (1992-08-01), Erbel et al.
patent: 5141738 (1992-08-01), Rasor et al.
patent: 5147631 (1992-09-01), Glagch et al.
patent: 5149319 (1992-09-01), Unger
patent: 5155215 (1992-10-01), Ranney
patent: 5171755 (1992-12-01), Kakufman
patent: 5205290 (1993-04-01), Unger
patent: 5209720 (1993-05-01), Unger
patent: 5230882 (1993-07-01), Unger
patent: 5260496 (1993-11-01), Meinert et al.
patent: 5271928 (1993-12-01), Schneider et al.
patent: 5281408 (1994-01-01), Unger
patent: 5284645 (1994-02-01), Long
patent: 5344393 (1994-09-01), Roth et al.
patent: 5354549 (1994-10-01), Klaveness et al.
patent: 5393524 (1995-02-01), Quay
Bommer, W. J., et al., Report of the American Society of Echocardiography: Contrast Echocardiography, Jun. 1984.
Ophir, J., et al., Contrast Agents In Diagnostic Ultrasound, Ultrasound in Medicine and Biology 15:319-333 (1989).
Schubert, K. V., et al., Microemulsifying Fluorinated Oils With Mixtures of Fluorinated and Hydrogenated Surfactants, Colloids and Surfaces: Physicochemical and Engineering Aspects 84:97-106 (1994).
American Heart Assoication, Abstracts of the 58th Scientific Sessions, Circulation 72: Oct. 1985 III-427.
Association of University Radiologists, Association of University Radiologists Proceedings of Annual Meeting, Journal of Clinical and Laboratory Research Investigative Radiology 17:4, Abstract 110 (1982).
Bleecker, H., et al., On the Application of Ultrsonic Contrast Agents for Blood Flowmetry and Assessment of Cardiac Perfusion, Journal of Ultrasound in Medicine, 9:461-471 (1990).
Bleeker, H., et al., Ultrasonic Characterization of Albunex, A New Contrast Agent, Journal Accoustical Society of America, 87:1792-1797 (1990).
Davis, P. L., et al., Echogenicity Cause By Stable Microbubbles In a Protein-Lipid Emulsion, The Journal of Clinical Ultrsound, 9:249-252, Jun. 1981.
De Jong, N., et al., Absorption and Scatter of Encapsulated Gas Filled Microspheres: Theoretical Considerations and Some Measurements, Ultrasonics, 30:95-103 (1992).
De Jong, N., et al., Principles and Recent Developments in Ultrsound Contrast Agents, Ultrasonics 29:324-330, Jul. 1991.
Epstein, P. S., et al., On The Stability of Gas Bubbles In Liquid-Gas Solutions, Journal of Chemical Physics 18:1505-1509, Nov. 1950.
Feinstein, Steven B., et al., Safety And Efficacy Of A New Transpulmonary Ultrasound Contrast Agent: Initial Multicenter Clinical Results, Journal of American College of Cardiology, 16:316-324, Aug. 1990.
Feinstein, Steven B., et al., Microcardial Contrast Echocardiography: Examination of Infracoronary Injections. Microbubble Diameters And Video Intensity Decay, American Journal of Physilogic Imaging 1:12-18 (1986).
Fobbe, V. F., et al., Farbkodierte Duplexsonographie Un Ultraschallkontrastmittel-Nachweis Von Renalen Perfusionsdefekten Im Tierexperiment, Fortschr. Rontgenstr. 154:242-245 (1991).
Handa, T., et al., Phospholipid Monolayers at the Triolein-Saline Interface: Production of Microemulsion Particles and Conversion of Monolayers to Bilayers, Biochemistry 29:2884-2890 (1990).
Kabalnov, A. S., et al., Safety And Efficacy of a New Transpulmonary Ultrsound Contrast Agent: Initial Multicenter Clincal Results, Journal of Fluorine Chemistry 50:271-284 (1990).
Keller, M. W., et al., Successful Left Ventricular Opacification Following Peripheral Venou Injection of Sonicated Contrast Agent: An Experimental Evaluation, American Heart Journal :570-575, Sep. 1987.
Long, David M., et al., Experiments with Radiopaque Perflurocarbon Emulsions for Selective Opacification of Organs and Total Body Angiography, Investigative Radiology 15:242-247 (1980).
Marshall, Nissim, Encyclodedie Des Gaz, Encyclopedia of Gas (1976).
Mattrey, Robert F., et al., Perfuorctylbromide: A Liver/Spleen-Specific and Tumor-Imaging Ultrsound Contrast Material, Radiology 145:759-762, Dec. 1982.
Meltzer, et al., Why do the Lungs Clear Ultrasonic Contrast?, Ultrasound In Medicine & Biology, 6:263-269 (1980).
Ohta, T., et al., Effect of the Contrast Agent and the Agitation Method on the Size, Number and Stability of Microbubbles: A Basic Experiment for the Myocardial Contrast Study, Japanese Journal of Medical Ultrasonics 18:318-325 (1991).
Schlief, R., Ultrasound Contrast Agents, Current Opinion In Radiology 3:198-207 (1991).
Serratrice, G., et al., Co-Colubilisation De Fluorocarbures Et D'Eau En Presence De Nouveaux Tensioactifs Non Ioniques Fluores, Journal Chim. Phys. 87:1969-1980 (1990).
Szonyi, F., et al., Syntheses De Tensioactifs F-Alkyles Non Ioniques Monodisperses, Journal of Fluorine Chemistry 36:195-209 (1987).
Verescon, Christian, et al., An Easy, Convenient Was of Describing The Stability of Fluorocarbon Emulsions, Journal de Chimie Physique 86:2111-2116 (1989).
Violante, M. R., et al., Particle Stabilized Bubbles For Enhanced Organ Ultrasound Imaging, Investigative Radiology 26:194-200, Nov. 1991.
Widder, Donald J., et al., Microbubbles As a Contrast Agent for Neurosonography and Ultrasound-Guided Catheter Manipulation: In Vitro Studies, AJR 147:347-352, Aug. 1986.
Zarif, Leila, et al., Synergistic Stabilization of Perfluorocarbon-Pluronic F-68 Emulsion by Perfluoroalkylated Polyhydroxylated Surgactants, Jaocks 66:10, Oct. 1989.
Ziskin, Marvin, C., et al., Contrast Agents For Diagnostic Ultrasound, Investigative Radiology 6:500-505 (1972).
Swanson, Dennis P., et al.; Pharmaceuticals in Medical Imaging, Radiopaque Contrast Media, Radiopharmaceuticals, Enhancement Agents for Magnetic Resonance Imaging and Ultrasound; Macmillan Publishing Co., Chapter 22, pp. 682-685, (1990).
Meltzer, Richard S., et al., Transmission Of Ultrasonic Contrast Through the Lungs, Ultrasound in Medicine and Biology, vol. 7, No. 4, pp. 377-384, 1981. Printed in Great Britain.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ultrasound contrast media comprising perfluoropentane and perflu does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ultrasound contrast media comprising perfluoropentane and perflu, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultrasound contrast media comprising perfluoropentane and perflu will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1927091

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.