Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-05-05
1999-11-23
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
252302, A61K 31385
Patent
active
059901535
ABSTRACT:
A pharmaceutical composition comprising an ultrasonicated formulation of .alpha.-lipoic acid and an aqueous solution which may also contain other antioxidants and/or metal chelators is disclosed.
Also disclosed is a method of ultrasonically preparing pure or mixed micelles of lipid-soluble antioxidants and .alpha.-lipoic acid in aqueous solutions for intravenous delivery to mitigate microvascular dysfunction in hemorrhagic shock and other conditions of acute microvascular injury.
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Samson Frederick E.
Wood John G.
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