Ultrasonically modulated polymeric devices for delivering compos

Details Ultrasonically modulated polymeric devices for delivering compos Ultrasonically modulated polymeric devices for delivering compos

1986-11-28

1988-10-25

Rosenbaum, Mark

Solid material comminution or disintegration

Processes

241 2, 241 30, 222 1, B02C 1918

Patent

active

047798068

ABSTRACT:
A composition such as a biologically active substance is delivered upon demand from a polymeric matrix by exposing the polymeric matrix containing the composition to ultrasonic energy.

REFERENCES:
patent: 3206755 (1965-09-01), Friedman
patent: 3207198 (1965-09-01), Beeson et al.
patent: 3464413 (1969-09-01), Goldfarb et al.
patent: 3474777 (1969-10-01), Figge et al.
patent: 3558066 (1971-01-01), Alliger
"Controlled Drug Release by Ultrasound Irradiation", Miyazaki et al., Chem. Pharm. Bull., 33(1), 428-431 (1985).
"Chemical and Physical Structure of Polymers as Carriers for Controlled Release of Bioactive Agents: A Review", Langer et al., Journal of Macromolecular Science, Reviews on Macromolecular Chemistry and Physics, C23(1), 61-126 (1983).
PCT Application No. WO82/03568, 10-1982.

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