Ultrasonic treatment of glaucoma

Surgery: kinesitherapy – Kinesitherapy – Ultrasonic

Reexamination Certificate

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C606S027000, C606S028000

Reexamination Certificate

active

08043235

ABSTRACT:
A method of treating glaucoma is described herein. The method includes the steps of providing an ultrasonic device that emits ultrasonic energy, holding the ultrasonic device at a location external to the trabecular meshwork, transmitting the ultrasonic energy at a frequency to a desired location for a predetermined time, causing biochemical changes to be initiated within the eye that may include triggering a presumed integrin response that initiates biochemical changes typified by but not limited to cytokines, enzymes, macrophage activity and heat shock proteins, and dislodging material built up in the trabecular meshwork.

REFERENCES:
patent: 4350917 (1982-09-01), Lizzi
patent: 4484569 (1984-11-01), Driller
patent: 4531934 (1985-07-01), Kossovsky
patent: 4561019 (1985-12-01), Lizzi
patent: 4729373 (1988-03-01), Peyman
patent: 4858124 (1989-08-01), Lizzi
patent: 5080101 (1992-01-01), Dory
patent: 5209221 (1993-05-01), Riedlinger
patent: RE34663 (1994-07-01), Seale
patent: 5458130 (1995-10-01), Kaufman
patent: 5636635 (1997-06-01), Massie et al.
patent: 5865742 (1999-02-01), Massie
patent: 6039689 (2000-03-01), Lizzi
patent: 6162193 (2000-12-01), Ekberg
patent: 6352519 (2002-03-01), Anis
patent: 6416740 (2002-07-01), Unger
patent: 6433464 (2002-08-01), Jones
patent: 6544254 (2003-04-01), Bath
patent: 6576875 (2003-06-01), Kleffner et al.
patent: 6618620 (2003-09-01), Freundlich et al.
patent: 6652459 (2003-11-01), Payne
patent: 6679855 (2004-01-01), Horn
patent: 6685657 (2004-02-01), Jones
patent: 6764439 (2004-07-01), Schaaf
patent: 6979328 (2005-12-01), Baerveldt
patent: 7083591 (2006-08-01), Cionni
patent: 7094225 (2006-08-01), Tu
patent: 7104958 (2006-09-01), Crutchfield et al.
patent: 2001/0014780 (2001-08-01), Martin et al.
patent: 2002/0039594 (2002-04-01), Unger
patent: 2002/0111608 (2002-08-01), Baerveldt
patent: 2002/0159952 (2002-10-01), Unger
patent: 2003/0088260 (2003-05-01), Smedley
patent: 2003/0097151 (2003-05-01), Smedley
patent: 2004/0030269 (2004-02-01), Horn
patent: 2004/0049105 (2004-03-01), Crutchfield et al.
patent: 2004/0050392 (2004-03-01), Tu et al.
patent: 2004/0091541 (2004-05-01), Unger
patent: 2005/0249667 (2005-11-01), Tuszynski et al.
patent: 2006/0047263 (2006-03-01), Tu
patent: 2006/0106370 (2006-05-01), Baerveldt
patent: 2006/0106424 (2006-05-01), Bachem
patent: 2006/0173437 (2006-08-01), Robin
patent: 2006/0217741 (2006-09-01), Ghannoum
patent: 2008/0051680 (2008-02-01), Luebcke
patent: 2008/0177220 (2008-07-01), Lindgren et al.
patent: 2008/0286255 (2008-11-01), Schwartz et al.
patent: 2010/0152626 (2010-06-01), Schwartz
patent: 2010/0260669 (2010-10-01), Yun et al.
patent: 2011/0077626 (2011-03-01), Baerveldt et al.
patent: 2011/0081333 (2011-04-01), Shantha et al.
patent: 2011/0092781 (2011-04-01), Gertner
patent: 2011/0092880 (2011-04-01), Gertner
patent: 2011/0118600 (2011-05-01), Gertner
patent: 2631545 (1989-11-01), None
patent: 2006021651 (2006-03-01), None
F. Valot et al., Treatment of glaucoma with high intensity focused ultrasound, International Opthalmology 13: 167-170 (1989).
C.C. Sterk et al., The effect of therapeutic ultrasound on the average of multiple intraocular pressures throughout the day in therapy-resistant glaucoma, Graefe's Arch Clin Exp Opthalmol (1989) 227; 36-38.
Extended European Search Report dated Sep. 10, 2009, which includes the supplementary European search report and the European search opinion, for related European Application No. 07814316.1.
Wang N, Chintala SK, Fini ME, Schuman JS; Ultrasound activates the TM ELAM-1/IL-1/NF-kappaB response: a potential mechanism for intraocular pressure reduction after phacoemulsification; Invest Ophthalmol Vis Sci. May 2003; 44(5):1977-81.
Bradley JM, Anderssohn AM, Colvis CM, Parshley DE, Zhu XH, Ruddat MS, Samples JR, Acott TS; Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression byIL-1 and TNF; Invest Ophthalmol Vis Sci. 2000; 41:422-430.
Hosseini M, Rose AY, Song K, Bohan C, Alexander JP, Kelley MJ, Acott TS; IL-1 and TNF induction of matrix metalloproteinase-3 by c-Jun N-terminal kinase in trabecular meshwork; Invest Ophthalmol Vis Sci. Apr. 2006; 47(4):1469-76.
Pang IH, Hellberg PE, Fleenor DL, Jacobson N, Clark AF; Expression of matrix metalloproteinases and their inhibitors in human trabecular meshwork cells; Invest Ophthalmol Vis Sci. Aug. 2003; 44(8):3485-93.
Alexander JP, Acott TS; Involvement of the Erk-MAP kinase pathway in TNFalpha regulation of trabecular matrix metalloproteinases and TIMPs; Invest Ophthalmol Vis Sci. Jan. 2003; 44(1):164-9.
Kelley MJ, Rose A, Song K, Lystrup B, Samples JW, Acott TS; p38 MAP kinase pathway and stromelvsin regulation in trabecular meshwork cells; Invest Ophthalmol Vis Sci. Jul. 2007; 48(7):3126-37.
Kelley MJ, Rose AY, Song K, Chen Y, Bradley JM, Rookhuizen D, Acott TS; Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork; Invest Ophthalmol Vis Sci. Jun. 2007;48(6):2634-43.
Office Action issued on May 25, 2010, by Chinese Intellectual Property Office in related Chinese Patent Application No. 200780035161.2.
Luna C, Li G, Liton PB, Qiu J, Epstein DL, Challa P, Gonzalez P; Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells; Food Chem Toxicol. Jan. 2009; 47(1):198-204. Epub Nov. 6, 2008.
Alexander JP, Acott TS; Involvement of protein kinase C in TNFalpha regulation of trabecular matrix metalloproteinases and TIMPs; Invest Ophthalmol Vis Sci. Nov. 2001; 42(12):2831-8.
Fleenor DL, Pang IH, Clark AF; Involvement of AP-1 in interleukin-1alpha-stimulated MMP-3 expression in human trabecular meshwork cells; Invest Ophthalmol Vis Sci. Aug. 2003;44(8):3494-501.
Written Opinion issued in related Singapore Application No. 200901271-7, provided by the Austrian Patent Office as Search and Examination Authority, with a mailing date of May 19, 2010.
Bradley, John M.B., et al., “Effects of Mechanical Stretching on Trabecular Matrix Metalloproteinases”, Investigative Ophthalmology & Visual Science, Jun. 2001, vol. 42 No. 7.
“Cellular Tolerance to Pulsed Hyperthermia”, by D. M. Simanovskii, et al., Physical Review, Jul. 24, 2006.
Effect of Ultraviolet Irradiation Upon the Cutaneous Pain Threshold, by M. Lipkin, et al., Journal of Applied Physiology May 1955 vol. 7 No. 6 683-687.
“Cytokine induction by 41.8°C whole body hyperthermia”, by H. Ian Robins, et al., Cancer Letters, vol. 97, Issue 2, Nov. 6, 1995, pp. 195-201.
“Stress Induced Changes in Lymphocyte Subpopulations and Associated Cytokines During Whole Body Hyperthermia of 41.8-42.2°C” O. Ahlers, et al., Eur J Appl Physiol (2005) 95: 298-306.
“Heat Shock Proteins and Regulation of Cytokine Expression”, by Y. Xie, C.M. Cahill, A. Asea, P.E. Auron, and S.K. Calderwood, Infectious Diseases in Obstetrics and Gynecology 7:26-30 (1999).
“Effects of Local and Whole Body Hyperthermia on Immunity”, by Gian Franco Baronzio, et al. can be found in the Madame Curie Bioscience Database [Internet], Austin (TX): Landes Bioscience; 2000. It can be found on the Internet at http://www.ncbi.nlm.nih.gov/books/NBK6083/.
“Heat Shock Co-Activates Interleukin-8 Transcription”, by Ishwar S. Singh, et al., Am J Respir Cell Mol Biol, Aug. 2008; 39(2): 235-242.
Preliminary Amendment dated Jun. 5, 2009, filed in related U.S. Appl. No. 11/842,909.
Office Action dated Jan. 12, 2010, issued in in related U.S. Appl. No. 11/842,909.
Amendment/Response to Office Action dated Mar. 16, 2010, filed in related U.S. Appl. No. 11/842,909.
Final Office Action dated Jun. 11, 2010, issued in in related U.S. Appl. No. 11/842,909.
Examiner's Interview Summary dated Dec. 7, 2010, issued in in related U.S. Appl. No. 11/842,909.
Amendment/Response to Office Action dated Dec. 9, 2010, filed in related U.S. Appl. No. 11/842,909.

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