Surgery – Truss – Pad
Patent
1987-10-01
1988-10-04
Jawoski, Francis J.
Surgery
Truss
Pad
424 2, 530363, 530427, A61B 1000
Patent
active
047749580
ABSTRACT:
An ultrasonic imaging agent is formed by subjecting an aqueous protein solution to high frequency sonication while heating the solution sufficiently to denature portions of the protein, thereby forming a dispersion of microbubbles stabilized by denatured protein. In a preferred embodiment, the protein solution is formed from human serum albumin, and the formed microbubbles have a relatively uniform size in the 2 to 5 micron range, suitable for imaging of pulmonary or small organ vasculature.
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Tickner, E. G., et al., "Noninvasive Assessment of Pulmonary Hypertension Using the Bubble Ultrasonic Resonance Pressure (BURP) Method", National Technical Information Svc. Dept. #HR-62917-1A, Apr., 1977.
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