Ultrasonic freeze ablation catheters and probes

Details Ultrasonic freeze ablation catheters and probes Ultrasonic freeze ablation catheters and probes

1990-12-20

1992-08-18

Aschenbrenner, Peter A.

Surgery

Instruments

Cyrogenic application

606 21, 606 24, A61B 1736

Patent

active

051394960

ABSTRACT:
Probes for medical surgery and flexible catheters for internal tissue ablation in which the tissue cells are frozen and deadened and yet extreme supercooling of tissue below the tissues' melting point is not required. The tissue cells are moderately supercooled by the probe or catheter and freezing of the cells is caused by cavitation nucleation of ice particles within the cells induced by a low power ultrasonic wave generator. The ultrasonic energy causes well distributed nucleation in the supercooled tissue cells and, as a result, the cells rapidly freeze and, due to such freezing, expand and burst their membranes.

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patent: 3913581 (1975-10-01), Ritson et al.
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patent: 4275734 (1981-06-01), Mitchiner
patent: 4528979 (1985-07-01), Marchenko et al.
patent: 4946460 (1990-08-01), Merry et al.

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