Ultrasonic force differentiation assay

Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using sonic or ultrasonic energy

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

422 69, 422 63, 422128, 422 99, 422102, 422236, 436501, 436518, 436526, 436528, 436534, 436536, 436806, 436824, 20415742, 20415762, 209214, 210222, 210223, 210695, G01N 2100, G01N 3096, G01N 33543, G01N 33553, B01D 3506

Patent

active

06086821&

ABSTRACT:
An ultrasonic energy source is used to provide a variable force for measuring the binding forces between molecular entities and for sensing the presence of an analyte in a test sample. The device includes a surface that has a first binding member attached thereto and one or more particles that have a second binding member attached thereto. A reaction vessel is provided for exposing the surface to the particles whereby, if the first binding member has a binding affinity for the second binding member, a complex is formed between individual first binding members and individual second binding members and the particles thereby become immobilized with respect to the surface. The ultrasonic energy source is positioned for applying a variable ultrasonic force onto the surface, and the position of the particles is monitored as the intensity of the ultrasonic force is varied.

REFERENCES:
patent: 4467653 (1984-08-01), Turbe
patent: 4484569 (1984-11-01), Driller et al.
patent: 4523122 (1985-06-01), Tone et al.
patent: 4571087 (1986-02-01), Ranney
patent: 4575485 (1986-03-01), Sizto et al.
patent: 4615984 (1986-10-01), Stoker
patent: 5343109 (1994-08-01), Mockl
patent: 5406851 (1995-04-01), Li
patent: 5445970 (1995-08-01), Rohr
patent: 5445971 (1995-08-01), Rohr
patent: 5666325 (1997-09-01), Belser et al.
patent: 5735280 (1998-04-01), Sherman et al.
patent: 5770461 (1998-06-01), Sakazume et al.
patent: 5779892 (1998-07-01), Miltenyi et al.
patent: 5853994 (1998-12-01), Gopinathan et al.
patent: 5912182 (1999-06-01), Coakley et al.
patent: 5921929 (1999-07-01), Goll et al.
Haga et al, "Effect of Ultrasonic Irradiation on the Dissociation of Anti-Antibody Complexes. Application to Homogeneous Enzyme Immunoassay", Chem. Pharm. Bull. 35(9) (1987), pp. 3822-2830).
Chen et al, "Ultrasound-Accelerated Immunoassay as Exemplified by Enzyme Immunoassay of Choriogonadotropin", Clinical Chemistry, 30, (1984), pp. 1446-1451.
Tarcha et al, "Absorption-enchanced Solid-Phase Immunoassay Method Via Water-Swellable Poly(acrylamide) Microparticles" Journal of Immunological Methods, 125 (1989) pp. 243-249.
Thomas et al, Measurement of Antigen Concentration by an Ultrasound-Enhanced Latex Immunoagglutination Assay, Ultrasound in Med. & Bio, vol. 22, No. 9, (1996), pp. 1277-1284.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ultrasonic force differentiation assay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ultrasonic force differentiation assay, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultrasonic force differentiation assay will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-538879

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.