Ultrasonic enhanced immuno-reactions

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436518, 436536, 436824, G01N 3353, G01N 33543

Patent

active

045754853

ABSTRACT:
Rates of binding between members of a specific binding pair, e.g., ligand-receptor, are greatly enhanced by short-term ultrasonication of an aqueous medium containing the specific binding pair. The enhanced rates find particular use in specific binding protein assays.

REFERENCES:
patent: 4410634 (1983-10-01), Cooper et al.
patent: 4477576 (1984-10-01), Deutsch et al.
High Technology, Mar. 1983, Perspectives: "Tiny Bubbles Promote Chemical Reactions".
Berezin et al., from Biomedical Applications of Immobilized Enzymes and Proteins, vol. 2, Ed. Chang, Plenum Press, NY, 1979, 237-251.

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