Ultrasmall, non-aggregated porous particles of uniform size for

Details Ultrasmall, non-aggregated porous particles of uniform size for Ultrasmall, non-aggregated porous particles of uniform size for

1995-06-05

1998-04-21

Kumar, Shailendra

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

1286622, 210639, 210709, 210729, 423495, 424 95, 424 951, 424 952, 424495, 514410, 514951, 514965, 560 45, 562455, A61K 914

Patent

active

057415226

ABSTRACT:
This invention relates to the preparation, composition and applications of suspensions of ultra-small, substantially non-aggregated, non-crystalline particles of predetermined uniform size which, when suspended in a liquid, contain entrapped gaseous bubbles. These gaseous bubble particles are prepared by simultaneous co-precipitation of two compounds. In accordance with the present invention, the two compounds chosen for co-precipitation are such that one is substantially more soluble than the other in a given vehicle. When this vehicle is used for washing the co-precipitated particles, part of the soluble material is dissolved leaving a porous matrix. The porous particles then are dried and stored. The porous particles, which can be resuspended immediately prior to use, contain entrapped gas in the evacuated crevices or pores which is not displaced for a period of time because of surface tension of the suspending vehicle. These ultrasmall, substantially non-aggregated porous particles therefore can be used to advantage as ultrasound contrast agents as well as other applications.

REFERENCES:
patent: 4997454 (1991-03-01), Violante et al.

Affiliated with

Also associated with

Rating

Ultrasmall, non-aggregated porous particles of uniform size for does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ultrasmall, non-aggregated porous particles of uniform size for , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultrasmall, non-aggregated porous particles of uniform size for will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2055447