Ultrapurification of factor IX and other vitamin k-dependent pro

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530380, 530381, 530382, 530383, 530413, 424 9463, A61K 3514, A61K 3800, C07K 100

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active

056398573

ABSTRACT:
A method of recovering active, highly purified and concentrated vitamin K-dependent proteins from plasma, concentrate or mixtures of proteins produced by recombinant DNA technology using an immunoadsorbent comprising a monoclonal antibody, and the active, highly purified and concentrated vitamin K-dependent protein produced by the method.

REFERENCES:
patent: 441794 (1890-10-01), Schwinn et al.
patent: 3560475 (1971-02-01), Fekete et al.
patent: 3920625 (1975-11-01), Anderson et al.
patent: 4081432 (1978-03-01), Delente et al.
patent: 4361509 (1982-11-01), Zimmerman et al.
patent: 4447416 (1984-05-01), Menache-Aronson et al.
patent: 5055557 (1991-10-01), Zimmerman
Osterud et al, J. Biol. Chem., vol. 253, pp. 5946-5951, 1978.
Goodall et al, Blood, vol. 59, No. 3, pp. 664-670, Mar. 1982.
Scopes, New York Springer-Verlag, pp. 132-135 and 194-200, 1982.
Hasko et al, Proceedings of the Ninth Annual Symposium on Blood Transfusion, Groninger, Netherlands, pp. 105-114, 1984.
Lieberman et al, Proc. Natl. Acad. Sci. USA, vol. 82, pp. 3879-3883, Jun. 1985.
Goodall et al "Affinity Depletion and Affinity Purification of Human Factor IX By Monoclonal Antibodies, Protides of the Biological Fluids, Proceedings of the 13th Colloquium," vol. 30, Feb. 1983, pp. 403-407, Pergamon Press, Oxford, Great Britain.
Goodall et al "Preparation of Factor IX Deficient Human Plasma . . . ", Blood, vol. 59, No. 3, Mar. 1982), pp. 664-670.
Osterud et al "Human Blood Coagulation Factor IX", J. Biol. Chem., 253:5946-5951.
Goodall, A.H., et al Biological Abstracts, vol. 74, No. 7, 1982, p. 4595, Abstract No. 44283, Philadelphia, PA.
Lewis, et al., Biochemistry. vol. 22, No. 4, 15 Feb. 1983, pp. 948-554, Amer. Chem. Society, New York.
Vehar, et al Nature 312-337-342 (1984).
Creighton, T.E. Proteins, W.H. Freeman & Co., New York (1983) pp. 78-79.
Brown et al, J. Biol. Chem., 255-5980-4983 (1980).
Miletich et al, Methods of Enzymology, 80:221-228 (1982).
Rotblat et al, Thrombosis and Haemostasis, 46(1) 1-478 (Jul. 12, 1981), Abstract No. 1055, p. 339.
Hagop Bessos et al, Thrombosis and Haemostatsis, F.K. Schattauer Verlag GmbH (Stuttgart) pp. 86-89 (1986).
Broze, Jr. et al "Purification and Properties of Human Coagulation Factor VII", The Journal of Biological Chemistry, vol. 255, No. 4, pp. 1242-1247, Feb. 25, 1990.
Scopes, R. Protein Purification, New York Springer-Verlag, pp. 132-135 and 194-200 (1982).
Flengsrud, R. "Purification and Some Characteristics of the Human Coagulation Factor VII", Eur. J. Biochem., 98:453-464, (1979).

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