Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1986-08-13
1989-03-21
Lusignan, Michael
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424127, 424154, 514891, A61K 920, A61K 3300, A61K 3306
Patent
active
048141771
ABSTRACT:
A calcium citrate composition having a bulk density greater than about 1.1 g/cc. Citric acid and a calcium compound are mixed to produce a mixture having a calcium compound/citric acid molar ratio of about 1.5. A hydrated mixture percent is produced by agitatively adding water to the mixture, although when desired the calcium compound, citric acid and water may
REFERENCES:
patent: 3105792 (1963-10-01), White
patent: 3653914 (1972-04-01), Schmitt
patent: 4107346 (1978-08-01), Kravitz
patent: 4185093 (1980-01-01), Carnes et al.
patent: 4214996 (1980-07-01), Buddemeyer et al.
patent: 4289750 (1981-09-01), Kopp et al.
patent: 4405596 (1983-09-01), Helbig et al.
patent: 4551342 (1985-11-01), Nakel et al.
patent: 4614648 (1986-09-01), Bru
patent: 4772467 (1988-09-01), Pak
Packett et al., date unavailable, "Mineral Studies in Ovine Phosphatic Urolithiasis", pp. 1716-1720.
Skillman (Consultant, Feb. (1984)).
Hunt and Johnson (Digestive Dis. and Sci., 28:417 (1983)).
Unlisted Drugs (1976), reference C.
Rote Liste (1961).
Pogainis and Shaw (Proc. S. D. Acad. Sci., XXXVI, p. 56 (1957)).
Chatterjee and Dhar (J. Phys. Chem., 28:1009 (1924)).
Sep. 11, 1986 News Release from Proctor and Gamble.
Bonnick (Letter to Newsweek, Feb. 17, 1986).
Kolata (Science, 233:519, (1986)).
Bishop Article from the Wall Street Journal (1986).
Abstract by Riggs et al. (1986).
Abstract by Christiansen et al. (J. Bone Min. Res., 1 (1986)).
Abstract by Markovic et al. (1986).
Brody (NY. Times, Dec. 17, 1985).
Pekkanen (Reader's Digest, Nov. 1985).
Rubin Newspaper Clipping (Austin American Statesman, Nov. 15, 1985).
Edelstein (1985) Article from Ladies Home Journal.
Harvey et al. (J. Clin. Endocrin. Met., 61:1223 (1985)).
Nicar and Pak (J. Clin. Endocrin, Met., 61:391 (1985)).
Sakhaee et al. (J. Clin. Endocrine, Met., 61:368 (1985)).
Bo-Linn et al. (J. Clin. Invest., 73:640 (1984)).
Consensus Development Conference Statement from the National Institute of Health (1984).
Kurtz et al. (Science, 222:1139 (1984)).
Ackley et al. (Am. J. Clin. Nutr., 38:457 (1983)).
Belizan (J. Am. Med. Ass'n., 249:1161 (1983 #1).
Belizan et al. (Am. J. Obstet. Gynecol., 146:175 (1983 #2)).
Nordenvall et al. (Eur. Urol., 9:35 (1983)).
McCarron et al. (Science, 217:267 (1982)).
Riggs et al. (New Eng. J. Med., 306:446 (1982)).
Strauss et al. (Am. J. Med., 72:17 (1982)).
Leskovar et al. (Urol. Int., 36:325 (1981)).
Butz and Rost (5th Symp. on Exptl. Urol., p. 243 (1980)).
Hartung et al. (idem (1980)).
Nordin et al. (Brit. Med. J., Feb. 16, 1980, p. 451).
Rudman et al. (N. Eng. J. Med., 303:657 (1980)).
Barilla et al. (Am. J. Med., 64:579 (1978)).
Heaney et al. (J. Lab. Clin. Med. 92:953 (1978)).
Pak (Calcium Nephrolithiasis, Plenum, N.Y., p. 5 (1978)).
Recker et al. (Ann. Int. Med., 87:649 (1977)).
Pak (Urolithiasis Res., Plenum, N.Y., p. 213 (1976)).
Pak et al. (J. Clin. Invest., 54:387 (1974 #1).
Pak et al. (N. Eng. J. Med., 290:175 (1974 #2)).
Peacock et al., (Brit. Med. J., Jun., p. 729 (1968)).
Clarkson et al. (Clin. Sci., 30:425 (1966)).
McDonald et al. (Clin. Sci., 26:27 (1964)).
Dialog Search of the Patent and Scientific Literature.
Packett, et al. (1968) J. Animal Science 27:1716-1721.
Alexandrides George
Pak Charles Y. C.
Walsdorf Neill B.
Board of Regents University of Texas System
Lusignan Michael
Mission Pharmacal
LandOfFree
Ultradense and more soluble and bioavailable preparations of cal does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ultradense and more soluble and bioavailable preparations of cal, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ultradense and more soluble and bioavailable preparations of cal will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-476090