Ultra-sensitive temperature sensing and calorimetry

Details Ultra-sensitive temperature sensing and calorimetry Ultra-sensitive temperature sensing and calorimetry

2008-01-16

2011-12-13

Mui, Christine T (Department: 1774)

Chemistry: analytical and immunological testing

Measurement includes temperature change of the material...

C422S051000, C422S050000

Reexamination Certificate

active

08076151

ABSTRACT:
Methods and apparatus for ultra-sensitive temperature sensing and calorimetry. Radiation is directed at a thin electrically conductive film having one or more small apertures. The incident radiation excites surface plasmons on a first surface of the electrically conductive film, and energy associated with the surface plasmons couples to an opposite surface of the electrically conductive film, where surface plasmon-enhanced radiation (SPER) is emitted from the aperture(s). A temperature-sensitive fluid or solid dielectric material is disposed contiguous with at least a portion of the electrically conductive film, such that a temperature change in the dielectric material alters a resonance condition for the SPER. Measurable changes in the SPER due to altered resonance conditions provide for an ultrasensitive temperature sensor that can detect small temperature changes in the dielectric material. The disclosed methods and apparatus may be used for a variety of applications including, but not limited to, nanoscale to microscale calorimetry for pharmaceutical and biotechnology products, combustion sensing, explosive detection, and biotoxin monitoring.

REFERENCES:
patent: 2003/0036204 (2003-02-01), Stark
patent: 2005/0260653 (2005-11-01), Labaer
patent: 2006/0159585 (2006-07-01), Torres et al.
patent: 1686360 (2006-08-01), None
Herminghaus et al., “Surface Plasmon Enhanced Transient Thermoreflectance,”Appl. Phys. A 51:350-353 (1990).
International Written Opinion for PCT/US2008/000580 mailed Jul. 30, 2009.
International Search Report for PCT/US2008/000580 mailed Sep. 26, 2008.

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