Ulcer treating composition comprising sufalcrate and antibiotic

Details Ulcer treating composition comprising sufalcrate and antibiotic Ulcer treating composition comprising sufalcrate and antibiotic

1995-11-17

1998-01-13

Krass, Frederick

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424493, 424499, 514 24, 514 53, A61K 3170

Patent

active

057076537

ABSTRACT:
Pharmaceutical compositions comprising an antibiotic adsorbed onto a disaccharide polysulfate-aluminum compound such as sucralfate are effective for the treatment of ulcers. The composition adherently coats the ulcer, protecting it while imparting an antibiotic activity which accelerates healing.

REFERENCES:
patent: 5538954 (1996-07-01), Koch et al.
Yokel et al, "Selective Adherence of A Sucralfate-Tetracycline Complex to Gastric Ulcers: Implications for the Treatment of Helicobacter Pylori", Biopharmaceutics and Drug Disposition, vol. 16, pp. 475-479, 1995.
Derwent Abstracts 90-377786, "Basic Aluminum Sucrose Sulphate Compositions", Dec. 1990.

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