Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-12-09
1996-08-06
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 51, 514 63, 514274, A61K 3170, A61K 31695, A61K 31505
Patent
active
055434010
ABSTRACT:
A method of rescuing healthy cells of a cancer patient being treated with antipyrimidine antitumor compounds, or related compounds. Rescue is accomplished by administering UDPG after administering the antipyrimidine antitumor compound preferably with BAU administration.
REFERENCES:
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Groeningen et al, "Reversal of 5-Fluorouracil Induced Myelosuppression by Prolonged Administration of High-Dose Uridine", Reports, Journal of the National Cancer Institute, vol. 81, No. 2, Jan. 18, 1989, p. 157.
Colofiore et al, "Effect of Uridine Diphosphoglucose on Levels of 5-Phosphoribosyl Pyrophosphate and Uridine Triphosphate in Murine Tissues", Pharmaceutical Research, vol. 6, No. 10, 1989, pp. 863-866.
Boehringer Mannheim Italia SpA
Rollins John W.
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