Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1995-06-07
1997-11-04
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435212, 435219, 43525233, 435243, 4353201, 435 6, 536 232, 536 234, C12N 120, C12N 950, C12N 948, C12N 100
Patent
active
056839049
ABSTRACT:
The disclosure relates to a generic class of ubiquitin-specific proteases which specifically cleave at the C-terminus of the ubiquitin moiety in a ubiquitin fusion protein irrespective of the size of the ubiquitin fusion protein. More specifically, the disclosure relates to ubiquitin-specific proteases of this class which have been isolated from a cell. The disclosure also relates to isolated DNA sequences encoding the proteases of this class.
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Baker Rohan T.
Tobias John W.
Varshavsky Alexander
Farrell Kevin M.
Massachusetts Institute of Technology
Nashed Nashaat T.
Wax Robert A.
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