Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Transferases
Patent
1995-06-05
1998-12-15
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Transferases
435193, 514 12, A61K 3851, A61K 3800, C12N 910
Patent
active
058492860
ABSTRACT:
Human UCE 7, UCE 8 and UCE 9 polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods of utilizing such polypeptide for the treatment of the proliferation of malignant cells. Antagonists against such polypeptides and their uses as a therapeutic to treat Alzheimer's disease, atrophying skeletal muscle, African swine fever virus and apoptotic cell death are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in UCE 7, 8 and 9 nucleic acid sequences and the concentration of polypeptides encoded by such sequences.
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Adams Mark D.
Gentz Reiner
Ni Jian
Hobbs Lisa J.
Human Genome Sciences Inc.
Mullins J. G.
Olstein Elliot M.
Wax Robert A.
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