Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Patent
1995-06-07
1999-10-19
Hobbs, Lisa
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
435193, C12Q 148, C12N 910
Patent
active
059687614
ABSTRACT:
The present invention relates to drug screening assays which provide a systematic and practical approach for the identification of candidate agents able to inhibit ubiquitin-mediated degradation of a cell-cycle regulatory protein, such as p53, p27, myc, fos, MAT.alpha.2, or cyclins. The invention further relates to novel ubiquitin-conjugating enzymes, and uses related thereto.
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Berlin Vivian
Chiu Maria Isabel
Cottarel Guillaume
Damagnez Veronique
Draetta Giulio
Hobbs Lisa
Mitotix, Inc.
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