Tyrosine kinase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S312000, C544S363000, C546S157000

Reexamination Certificate

active

10489647

ABSTRACT:
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

REFERENCES:
patent: 5409930 (1995-04-01), Spada et al.
patent: 6306874 (2001-10-01), Fraley et al.
patent: 2003/0028018 (2003-02-01), Renhowe et al.
patent: WO 92/20642 (1992-11-01), None
patent: WO 97/06144 (1997-02-01), None
patent: WO 97/19927 (1997-06-01), None
patent: WO 97/44037 (1997-11-01), None
patent: WO 98/23613 (1998-06-01), None
patent: WO 00/09495 (2000-02-01), None
Emerging approaches to antiangiogenic therapies for treating cancer, posted Nov. 3, 2005 on http://www.nyas.org/ebriefreps/main.asp?intSubsectionID=3099 .
Chinese Science Bulletin, vol. 36, No. 24, pp. 2056-2060 (1991), by J. Meng, et al.
Science in China, vol. 36, No. 5, pp. 540-549 (1993), by J. Meng, et al.
Oncogene, vol. 6, pp. 1677-1683 (1991), by B. Terman, et al.
J. Clin. Invest, vol. 104, No. 11, pp. 1613-1620 (1991), by N. van Bruggen, et al.
Drug News Perspect, vol. 11, No. 5, pp. 265-270 (1998), by D. Greenberg.
Nature, vol. 407, pp. 242-248 (2000), by G. Yancopoulos, et al.
Nature, vol. 407, pp. 249-257 (2000), by P. Carmeliet, et al.
J. Heterocyclic Chem., vol. 28, pp. 1481-1484 (1991), by R. Wang, et al.
Nature Biotech., vol. 17, pp. 963-968 (1999), by V. Brower.
Nature Medicine, vol. 5, No. 6, pp. 623-628 (1999), by H. Gerber, et al.
Molecular Cell, vol. 4, pp. 915-924 (1999), by B. Eliceiri, et al.
Stem Cells, vol. 12, pp. 1-6 (1994), by T. Burke, Jr.
Platelets, vol. 10, pp. 285-292 (1999), by A Amirkhosravi, et al.
FEBS Letters, vol. 473, pp. 161-164 (2000), by M. Nakagawa, et al.
Endocrinology, vol. 141, No. 5 pp. 1667-1674 (2000), by M. Deckers, et al.
Oncogene, vol. 5, pp. 519-524 (1990), by M. Shibuya, et al.
J. Med. Chem., vol. 37, pp. 2129-2137 (1994), by M. Maguire, et al.
J. Med. Chem., vol. 42, pp. 5369-5389, by L. Hennequin, et al.
Cancer Research 64, pp. 751-756, Jan. 15, 2004, by L. Sepp-Lorenzino, et al.
Bioorganic & Medicinal Chemistry Letters 14, (2004), pp. 351-355, by M. Fraley, et al.
Current Medicinal Chemistry 11, (2004), pp. 709-719, by M. Fraley, et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Tyrosine kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tyrosine kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tyrosine kinase inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3824379

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.