Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-08-08
2006-08-08
Slobodyansky, Elizabeth (Department: 1652)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S196000, C435S198000, C435S252300, C435S320100, C435S325000
Reexamination Certificate
active
07087736
ABSTRACT:
The present invention provides a nucleic acid molecule encoding a tyrosine-DNA phosphodiesterase (TDP), and a related vector, host cell, polypeptide, antibody, antisense nucleic acid molecule, and ribozyme. Also provided are a method of altering the level of TDP in a cell, tissue, organ or organism, as well as the resulting cell, tissue, organ or non-human organism, as well as a method of identifying a TDP-resistant compound, a method of assessing TDP1 activity in an animal, and a method of assessing the efficacy of a topoisomerase I inhibitor.
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Nash Howard A.
Pouliot Jeffrey
Leydig , Voit & Mayer, Ltd.
Slobodyansky Elizabeth
The United States of America as represented by the Department of
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