Tyrosine derivatives and process for preparing the same

Details Tyrosine derivatives and process for preparing the same Tyrosine derivatives and process for preparing the same

1976-12-20

1977-11-08

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125R, A61K 3700, C07C10352

Patent

active

040576299

ABSTRACT:
Compounds having the formula: ##STR1## wherein R.sub.1 is phenyl or cycloalkyl and the phenyl may have at least one substituent selected from the group consisting of lower alkyl, lower alkoxy, amino and nitro; R.sub.2 is hydrogen or lower alkyl; A is --CH.sub.2 O-- or --CH.sub.2 CH(O-lower alkyl)-; n is zero (0) or one (1); when R.sub.1 together with (A).sub.n is unsubstituted phenyl, R.sub.2 is lower alkyl; and R.sub.3 is hydrogen or lower alkoxy, have anti-ulcerousaction.

REFERENCES:
patent: 3778427 (1973-12-01), Flouret
S. Bosen, Chem. Abst., vol. 76, 1972, pp. 14879z.
G. E. Clement, et al., J. Amer. Chem. Soc., 92, 1970, pp. 186-189.
B. Juodka, et al., Chem. Abst., 76, 1972, pp. 25561r.

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