Tyrosinase-activator protein fusion enzyme

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 234, 536 232, 4353201, 435189, 4352523, 43525233, 43525235, 935 47, C12N 902, C12N 120, C12N 1553, C12N 1562

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055299091

ABSTRACT:
The present invention relates to a nucleic acid sequence that encodes a fusion enzyme of tyrosinase and a tyrosinase activator protein. Further, the present invention also relates to the amino acid sequence which is encoded by the nucleic acid sequence of the fusion enzyme. The fusion enzyme may also include a linker positioned between the amino acid sequences of the tyrosinase and the tyrosinase activator protein. Still further, the present invention also relates to a vector useful for introducing the nucleic acid sequence encoding the fusion enzyme into an organism. Still further, the present invention relates to melanins made by the fusion enzyme and a method for making melanins using the fusion enzyme.

REFERENCES:
patent: 4898814 (1990-02-01), Kwon
Huber, et al., Nuc. Acids Res., vol. 15, No. 19, 1987, p. 8106.
Bernan, et al., Gene, vol. 37, 1985, pp. 101-110.
Lee, et al., Gene, vol. 65, 1988, pp. 71-81.
Huber, et al., Biochem., vol. 24, 1985, pp. 6038-6044.

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