Type F botulinum toxin and use thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C530S300000, C435S069100, C435S320100, C424S184100

Reexamination Certificate

active

07041792

ABSTRACT:
A polypeptide free of toxin activity providing protection againstbotulinumtype F toxin is provided. A fusion protein of a fragment of a toxin molecule and a purification moiety enabling purification of a fragment from solution and pharmaceutical compositions containing the polypeptide and the fusion protein are described.

REFERENCES:
patent: 5178859 (1993-01-01), Simon et al.
patent: 5736139 (1998-04-01), Kink et al.
patent: WO 9403615 (1994-02-01), None
patent: WO 9421684 (1994-09-01), None
patent: WO 94/21684 (1994-09-01), None
Lazar et al., Mol.Cell Bio. 8:1247-1252, 1988.
Burgess et al. J. Cell Bio. 111:2129-2138, 1990.
East et al, Curr. Microbio. 29:69-77, 08/94.
Jobling et al Mol Microbiol 517:1765-67, 1991.
Skolnick et al. Trends in Biotech. 18(1):34-39, 2000.
Thompson et al. FEMS Microbiol Lttrs. 108 175-82, 1993.
Wadsworth et al., Biochem J., 268:123-128, 1990.
Hatheway et al., Applied and Environmental Microbiol., 31(2):234-242, 1976.
Choh et al., PNAS 77(6):3211-14, 1980.
Sexton et al., J. of Immunol., 152(4):1861-72. 1994.
Campbell et al., J. Clin. Microbiol., 31, 2255-2262, 1993 and Genbank Accession No. X70821.
Elmore et al., Genbank Accession No. L35496, Aug. 23, 1994.
Montgomery et al., “Evaluation of Botulinum Type F Vaccine By Elisa”, Abstracts of the 95thGeneral Meeting of The American Society for Microbiology, 21-25 May 1995, Washington, D.C. USA, p. 289, XP002015937.
Sassenfeld, “Engineering Proteins for Purification”, Trends in Biotechnology, vol. 8, No. 4, Apr. 1990, pp. 88-93, XP000103110.
Zhou et al., “Expression and Purification of the Light Chain of Botulinum Neurotoxin A: A Single Mutation Abolishes its Cleavage of Snap-25 and Neurotoxicity After Reconstitution with the Heavy Chain”, Biochemistry, vol. 34, Nov. 1995, pp. 15175-15181, XP002015939.

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