Tylosin resistance-conferring gene, designated tlrC, for use in

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435 691, 435 91, 4351721, 4351723, 4352535, 435320, 435896, 536 27, 935 19, 935 29, 935 41, 935 56, 935 60, 935 75, 935 81, C12N 120, C12N 1500, C12N 700, C12P 2100, C12P 1934, C12R 154, C07H 1512

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048898090

ABSTRACT:
The tlrC gene is a novel tylosin resistance-conferring gene isolated from Streptomyces fradiae and used to construct a number of cloning vectors for use in Streptomyces. One such cloning vector, plasmid pSKC10, can be obtained in S. fradiae JS87 under the accession number NRRL 18072. S. fradiae JS87 is the preferred host when the tlrC gene is used to select tylosin-resistant Streptomyces transformants.

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