Tylosin resistance-conferring gene, designated tlrB, for use in

Details Tylosin resistance-conferring gene, designated tlrB, for use in Tylosin resistance-conferring gene, designated tlrB, for use in

1986-06-05

1989-11-07

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 68, 435 91, 4351721, 4354723, 435320, 435886, 536 27, 935 6, 935 29, 935 38, 935 56, 935 60, 935 75, C12N 120, C12N 1500, C12N 100, C12P 2100, C12P 1134, C12R 1465, C07H 1512

Patent

active

048792411

ABSTRACT:
The tlrB gene is a novel tylosin resistance-conferring gene isolated from Streptomyces fradiae and used to construct a number of cloning vectors for use in Streptomyces and related organisms. One such cloning vector, plasmid pSVB9, can be obtained in S. lividans under the accession number NRRL 18073. S. lividans is the preferred host when the tlrB gene is used to select tylosin-resistant Streptomyces transformants.

REFERENCES:
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