Tylosin macrolide antibiotics from streptomyces

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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424180, 536 71, 435100, A61K 3171, C07H 1708, C12P 1962

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active

044118929

ABSTRACT:
An antibiotic complex, consisting of two major components, has been isolated from fermentations of a new subspecies of Streptomyces albus culture. The two major components from the complex are two new macrolide antibiotics, which are active as antibacterial agents against certain gram-positive and gram-negative microorganisms.

REFERENCES:
patent: 4268665 (1981-05-01), Sakakibara et al.
patent: 4358584 (1982-11-01), Nash et al.
patent: 4366309 (1982-12-01), Ganguly et al.
Encyclopedia of Chemical Technology, Kirk-Othmer, Third Edition, vol. 2, John Wiley & Sons, 1978, p. 951.
The Merck Index, An Encyclopedia of Chemicals and Drugs, Ninth Edition, Merck & Co., Inc., Rahway, N.J., 1976, Entry 9486, p. 1260.

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