Two step method for preparation of controlled release formulatio

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 7802, 424 7808, 424 7831, 424484, 424489, 424501, C08J 928

Patent

active

051456753

ABSTRACT:
Active substances intended for topical application are incorporated in novel formulations in which they are retained as impregnants inside the pores of porous solid particles or microspheres. The pores form a continuous network open to the exterior of the particles, permitting outward diffusion of the impregnants at a controlled rate depending on the pore size. The impregnated particles are prepared by impregnation of preformed particles with the active substance.

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