Surgery – Miscellaneous – Methods
Patent
1994-12-05
1997-02-18
Sykes, Angela D.
Surgery
Miscellaneous
Methods
600 16, A61B 1900
Patent
active
056033370
ABSTRACT:
Heart failure may be treated by grafting a skeletal muscle around the heart in a procedure called cardiomyoplasty. The muscle graft is stimulated to contract in synchrony with the heart by a burst stimulator, and the procedure has been shown to have some benefits. However, the operative and early mortality is high (nearly 50% 2-year mortality). The present invention recognizes a fundamental limitation to the effectiveness of cardiomyoplasty when applied to a markedly enlarged heart, due to the length tension characteristics of muscle. A two-stage procedure is provided, whereby the enlarged heart is first treated with a mechanical cardiac assist pump to reduce it to near normal size. Then a second surgical procedure, in which an optimal length of muscle is grafted to the heart, is performed about 4-6 weeks later. The muscle to be grafted may be preconditioned by electrical stimulation within a pouch designed to prevent tissue adhesions, during the time that the heart is being reduced in size with mechanical assistance.
REFERENCES:
patent: 4403604 (1983-09-01), Wilkinson et al.
patent: 5256132 (1993-10-01), Snyders
patent: 5480436 (1996-01-01), Bakker et al.
Davol Rubber Co., "Complete Evisceration of Small Bowel . . . " 1959.
Chiu, "Using Skeletal Muscle for Cardiac Assistance", Scientific American Science & Medicine, Nov./Dec. 1994.
Lacyk John P.
Sykes Angela D.
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