Two-photon fluorescent probes for acidic vesicles in live...

Details Two-photon fluorescent probes for acidic vesicles in live... Two-photon fluorescent probes for acidic vesicles in live...

2011-06-07

2011-06-07

Weber, Jon P (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

C564S169000, C436S172000

Reexamination Certificate

active

07955815

ABSTRACT:
Provided are two-photon fluorescent probes for imaging acidic vesicles in live cells and tissue. The probes are represented byThe probes can selectively bind to vesicles in cytosol to emit two-photon excited fluorescence with high intensity. Therefore, the use of the probes enables effective imaging of acidic vesicles. Further provided is a method for imaging acidic vesicles in live cells and tissue using the probes.

REFERENCES:
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Kim et al. Two-Photon Fluorescent Probes for Acidic Vesicles in Live Cells and Tissue; Angew. Chem. Int. Ed., (2008) vol. 47, pp. 2231-2234.
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H. M. Kim, B. R. Kim, J. H. Hong, J.S. Park, K. J. Lee, Cho, B. R.Angew. Chem. Int. Ed. 2007, 46, 7445-7448.

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