Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Reexamination Certificate
2011-07-19
2011-07-19
Rao, Manjunath N (Department: 1656)
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
C530S323000, C530S317000, C435S007230
Reexamination Certificate
active
07981691
ABSTRACT:
An isolated polypeptide, Z domain, derived from B domain ofStaphylococcalprotein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of a covalent bridge between two modified amino acids in the polypeptide is provided here. Also provided are methods of using the two-helix binders.
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Hoerner Joshua Kendall
Syud Faisal Ahmed
Webster Jack Mathew
Zhang Rong
Gebreyesus Kagnew H
General Electric Company
Haeckl Jenifer E.
Rao Manjunath N
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