Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1992-06-01
1993-08-31
Niebling, John
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
204299R, G01N 2726, G01N 27447, B01D 5702
Patent
active
052405770
ABSTRACT:
Disclosed is a two-dimensional separation system, comprising a liquid chromatography column having an outlet port; a capillary electrophoresis capillary having an inlet end and an outlet end; buffer supply means for supplying buffer to the capillary; and valve means connecting the capillary inlet end to the chromatography column outlet port and to the buffer supply means, the valve means switchable between a first configuration providing fluid to the capillary inlet end from the buffer supply means and a second configuration providing fluid to the capillary inlet end from the chromatography column. Methods of carrying out two-dimensional separations employing the system are also disclosed.
REFERENCES:
patent: 4676897 (1987-06-01), Kuze et al.
patent: 4708782 (1987-11-01), Andresen et al.
Hideko Yamamoto et al. "Apparatus for coupled high-performance liquid chromatography and capillary electrophoresis in the analysis of complex protein mixtures" Journal of Chromatography 515 (1990) 659-666.
D. Kaniansky et al. "Some possibilities of combining high-performance liquid chromatography with isotachophoresis for the trace determination of ionogenic compounds present in complex matrices" Journal of Chromatography, 509 (1990) 271-282.
Michelle M. Bushey et al. Anal. Chem. 62, 161-167 (1990).
Randall G. Nielssen et al., Journal of Chromatography 480, 393-401 (1989).
Hideko Yamamoto et al., Journal of Chromatography 480, 277-283 (1989).
Paul D. Grossman, et al., Anal. Chem. 61, 1186-1194 (1989).
J. C. Giddings, Journal of High Resolution Chromatography & Chromatography Communications 319-323 (1987).
P. S. L. Janssen et al., Journal of Chromatography 470, 171-183 (1989).
Jonathan S. Green et al., Journal of Chromatography 352, 337-343 (1986).
Joe M. Davis et al., Anal. Chem., 57, 2168-2177 (1985).
Joe M. Davis et al., Anal. Chem. 57, 2178-2182 (1985).
Bushey Michelle M.
Jorgenson James W.
Niebling John
Starsiak Jr. John S.
University of North Carolina at Chapel Hill
LandOfFree
Two-dimensional high-performance liquid chromatography/capillary does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Two-dimensional high-performance liquid chromatography/capillary, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Two-dimensional high-performance liquid chromatography/capillary will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2295456