Tungsten clusters

Details Tungsten clusters Tungsten clusters

1995-07-20

1997-06-24

Nazario-Gonzalez, Porfirio

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

X-ray contrast imaging agent

556 57, 436173, A61K 4904, C07F 1100

Patent

active

056414722

ABSTRACT:
The present invention provides new tri-tungsten compounds of the general structure: ##STR1## wherein R.sup.1 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.2 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.3 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.4 is --(C.sub.k H.sub.1 Z.sub.m) or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.5 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.6 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; Z is a functional group attachable on aliphatic chains or aromatic rings; R.sup.7 is an anionic molecule, neutral molecule, --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.8 is an anionic molecule, neutral molecule, --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.9 is an anionic molecule, neutral molecule, --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; k is about 0-20; l is about 0-50; m is about 1-50; n is about 0-50; p is about 1-10; q is about 1-5; M is a counter positive or negative ion; and a is about -6-+6. W in the structure is the generally accepted one letter symbol for tungsten. Methods of imaging using compounds of the invention and processes for producing compounds of the invention are also disclosed.

REFERENCES:
Colton et al., Inorganic Chemistry, vol. 23, No. 26, pp. 4738-4742 (1984).
Colton et al., Inorganic Chemistry, vol. 23, No. 24, pp. 4033-4038 (1984).
Powell et al., Inorganic Chemistry, vol. 32, No. 19, pp. 4021-4029 (1993).

Affiliated with

Also associated with

Rating

Tungsten clusters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tungsten clusters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tungsten clusters will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-147615