Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-03-20
1998-11-03
Huff, Sheela
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 231, 536 235, 530350, 435 691, 435 693, 435 711, 4353201, 435273, 4352523, 935 22, 935 66, 935 67, 935 68, 935 69, 935 70, 935 71, 935 72, 514 44, C12Q 168, C07H 2102, C07H 2100, C07H 2104
Patent
active
058306609
ABSTRACT:
The present invention provides a human tumorigenesis protein (HTAP) and polynucleotides which identify and encode HTAP. In addition, the invention provides expression vectors and host cells, agonists, antibodies, and antagonists. The invention also provides methods for producing HTAP and for treating or preventing disorders associated with the expression of HTAP.
REFERENCES:
Haupt et al, Mol. Biol. Rep. vol. 17 p. 17 1992.
Helzlsouer, K.J. "Epidemiology, prevention, and early detection of breast cancer." Curr. Opin. Oncol. (1994) 6(6):541-548.
Harris, J.R. et al., "Breast cancer." N.Engl.J.Med. (1992) 327 (5):319-328.
Haupt, Y. et al., "Novel Zinc Finger Gene Implicated as myc Collaborator by Retrovirally Accerlerated Lymphomagenesis in E.mu.-myc Transgenic Mice." Cell (1991 65:753-763.
Lohuizen, M. et al., "Tumorigenesis by slow-transforming retroviruses-an update." Biochimica et Biophysica Acta. (1990) 1032:213-235.
Haupt, Y. et al., "Nucleotide sequence of bup, an upstream gene in the bmi-1 proviral insertion locus." Molecular Biology Reports (1992) 17:17-20. (GI 265569).
Haupt, Y. et al., (GI 265569) GenBank Sequence Database (Accession S54914), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Haupt, Y. et al., (GI 265568) GenBank Sequence Database (Accession S54914), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894.
Goli Surya K.
Hillman Jennifer L.
Billings Lucy J.
Huff Sheela
Incyte Pharmaceuticals Inc.
Mohan-Peterson Sheela
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