Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-04-24
2007-04-24
Shameem, Golam M. M. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S372500
Reexamination Certificate
active
10548827
ABSTRACT:
A compound having a xanthine oxidase inhibitory activity, such as 1-(3-cyano-4-neopentyloxyphenyl)pyrazole-4-carboxylic acid and the like, can be a drug for preventing cancer including colon cancer and the like, as an agent for suppressing tumorigenesis.
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T. Tanaka et al., “Chemoprevention of Azoxymethane-Induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1′-Acetoxychavicol Acetate”, Jpn. J. Cancer Res., vol. 88, pp. 821-830, Sep. 1997.
M. Ohnishi et al., “Chemopreventive Effect of a Xanthine Oxidase Inhibitor, 1′-Acetoxychavicol Acetate, on Rat Oral Carcinogenesis”, Jpn. J. Cancer Res., vol. 87, pp. 349-356, Apr. 1996.
J. Lin et al., “Inhibition of Xanthine Oxidase and NADPH Oxidase by Tea Polyphenols”, ACS Symposium Series, vol. 807, Free Radicals in Food, pp. 264-281, 2002.
Chu Yong
Mitsubishi Pharma Corporation
Shameem Golam M. M.
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