Tumor suppressor protein pRb2, related gene products, and DNA en

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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4352523, 4353201, 4351723, 435 911, 435849, 536 231, 536 235, 530350, 935 9, 935 29, 935 73, C12N 121, C12N 1512, C12N 1570

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054570492

ABSTRACT:
The invention provides a tumor suppressor protein of the retinoblastoma family (pRb2) which binds to the E1A transforming domain and to DNA encoding for the pRb2 protein.

REFERENCES:
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Giordano et al., "Human Cyclin A and the Retinoblastoma Protein Interact with Similar but Distinguishable Sequences in the Adenovirus E1A Gene Product," Oncogene 6, 481-485 (1992).
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