Tumor suppressor protein and nucleotide encoding same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C424S184100

Reexamination Certificate

active

07807626

ABSTRACT:
The invention provides a method for suppressing tumor cell growth in a patient, comprising: administering to the patient an effective amount of an expression vector including a polynucleotide encoding a tumor suppressor protein having SEQ ID NO: 1 under conditions wherein the expression vector incorporates itself into the tumor cell genome and inhibits cell proliferation or induces cell death.The invention further provides a method for a method for inhibiting tumor cell proliferation in a tumor cell population comprising: administering to the tumor cell population an amount of a composition comprising a tumor suppressor protein having SEQ ID NO: 1 effective to inhibit tumor cell proliferation therein.

REFERENCES:
patent: 2004/0043926 (2004-03-01), Gerlach et al.
Mellman I, 2006, The Scientist, 20(1): 47-56.
Kaiser (Science, 2006, 313, 1370).
Bodey et al, 2000, Anticancer Res, 20: 2665-2676.

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