Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-06-12
2010-10-05
Helms, Larry R. (Department: 1642)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S184100
Reexamination Certificate
active
07807626
ABSTRACT:
The invention provides a method for suppressing tumor cell growth in a patient, comprising: administering to the patient an effective amount of an expression vector including a polynucleotide encoding a tumor suppressor protein having SEQ ID NO: 1 under conditions wherein the expression vector incorporates itself into the tumor cell genome and inhibits cell proliferation or induces cell death.The invention further provides a method for a method for inhibiting tumor cell proliferation in a tumor cell population comprising: administering to the tumor cell population an amount of a composition comprising a tumor suppressor protein having SEQ ID NO: 1 effective to inhibit tumor cell proliferation therein.
REFERENCES:
patent: 2004/0043926 (2004-03-01), Gerlach et al.
Mellman I, 2006, The Scientist, 20(1): 47-56.
Kaiser (Science, 2006, 313, 1370).
Bodey et al, 2000, Anticancer Res, 20: 2665-2676.
Shiu Stephen Yuen Wing
Yao Kwok Ming
Cooper & Dunham LLP
Davis Minh-Tam
Helms Larry R.
Katz Robert D.
The University of Hong Kong
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