Tumor suppressor merlin and antibodies thereof

Details Tumor suppressor merlin and antibodies thereof Tumor suppressor merlin and antibodies thereof

1995-06-07

2000-06-20

Feisee, Lila

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351721, 4353201, 514 12, 935 62, 530350, 5303871, 5303873, 5303877, C07K 1482, C07K 1630, C12N 1512, A61K 4800

Patent

active

060776854

ABSTRACT:
A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin-associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.

REFERENCES:
patent: 5578462 (1996-11-01), Seizinger et al.

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