Tumor suppressor gene, p471NG3

Details Tumor suppressor gene, p471NG3 Tumor suppressor gene, p471NG3

2010-03-15

2011-11-29

Goddard, Laura B (Department: 1642)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100

Reexamination Certificate

active

08067563

ABSTRACT:
The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins.

REFERENCES:
patent: 6117633 (2000-09-01), Garkavtsev et al.
patent: 6297366 (2001-10-01), Gudkov et al.
patent: 6569662 (2003-05-01), Tang et al.
patent: 2005/0048623 (2005-03-01), Hillman et al.
patent: WO 97/21809 (1997-09-01), None
patent: WO 00/58473 (2000-10-01), None
patent: WO 01/07471 (2001-02-01), None
U.S. Appl. No. 60/121,891, filed Feb. 26, 1999, Harris et al.
Campbell, A., “Monoclonal antibody technology: the production and characterization of rodent and human hybridomas,”Laboratory Techniques in Biochemistry and Molecular Biology(1984(13 (1): 1-33.
Dauphin, et al., “Hypothetical protein (fragment),” XP002177545, Database Swissprot Online Entry/Acc. No. O60394, 1 page (Aug. 1, 1998).
Garkavtsev, et al., “The candidate tumour suppressor p33ING1cooperates with p53 cell growth control,”Nature(Jan. 1998) 391(15): 295-298.
Garkavtsev, et al., “Suppression of the novel growth inhibitor p33ING1promotes neoplastic transformation,”Nature Genetics(Dec. 1996) 14: 415-420.
Garkavtsev, et al., “Homo Sapiens Candidate Tumor Suppressor p33ING1 (ING1) mRNA,” Database GenBank Online Entry/Acc. No. AF044076, 2 pages, (Feb. 4, 1998).
Green, et al., “Homo Sapiens PAC Clone RP5-872F7 from 7q31,” Database GenBank Online Entry/Acc. No. AC004537, 28 pages (Feb. 3, 2000).
Invitrogen™ product information sheet for protein standards and ladders (Jan. 3, 2008) pp. 1-4.
Kultima, et al.,BMC Bioinformatics(2006) 7:475 internet pp. 1-27.
Nagashima, et al., “DNA Damage-Inducible Gen p33ING2 Negatively Regulates Cell Proliferation Through Acetylation of p53,”PNAS, vol. 98, No. 17, pp. 9671-9676, (Aug. 14, 2001).
Sambrook, et al.,Molecular Cloning, 2ndEd., Cold Spring Harbor Press (1989) pp. 18-47.
Saito, et al., “p24/ING1-ALT1 and p47/ING1-ALT2, Distinct Alternative Transcripts of p33/ING1,”J. Hum. Genet., (2000) vol. 45, Jpn Soc Hum Genet and Springer-Verlag, pp. 177-181.
Stein, et al.,Cancer Research(Apr. 2004) 64: 2805-2816.
Strausberg, et al., “qc48c10.x1 Soares—Pregnant—Uterus—NbHPU Homo Sapiens cDNA Clone IMAGE: 1712850 3′ Similar to TR:000532 000532 P33ING1. ;. mRNA Sequence.” XP002177544, Database EMBL Online Entry/Acc. No. AI129337, 2 pages, (Sep. 22, 1998).
Zips, et a., In vivo (2005) 19: 1-7.

Affiliated with

Also associated with

Rating

Tumor suppressor gene, p471NG3 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tumor suppressor gene, p471NG3, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tumor suppressor gene, p471NG3 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4280941