Tumor suppressor gene merlin

Details Tumor suppressor gene merlin Tumor suppressor gene merlin

1993-12-22

1998-01-13

Jagannathan, Vasu

Chemistry: molecular biology and microbiology

Vector, per se

435 691, 536 235, 536 241, C12N 1512, C12N 1500, C12N 1509

Patent

active

057078637

ABSTRACT:
A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin-associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.

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