Tumor suppressor gene, HIC-1

Details Tumor suppressor gene, HIC-1 Tumor suppressor gene, HIC-1

1995-05-25

1999-07-13

Walsh, Stephen

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

43525411, 4353201, 435325, 536 235, C12N 1512, C12N 115, C12N 121, C12N 510

Patent

active

059225904

ABSTRACT:
Polynucleotide and polypeptide sequences encoding a novel tumor suppressor, HIC-1 , are provided. Also included is a method for detecting a cell proliferative disorder associated with HIC-1. HIC-1 is a marker which can be used diagnostically, prognostically and therapeutically over the course of such disorders.

REFERENCES:
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Crosby et al. The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family. Molecular and Cellular Biology. vol. 11, pp. 3835-3841, 1991.
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