Tumor suppressor gene, HIC-1

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 231, C12Q 168, C07H 2102

Patent

active

058467122

ABSTRACT:
Polynucleotide and polypeptide sequences encoding a novel tumor suppressor, HIC-1, are provided. Also included is a method for detecting a cell proliferative disorder associated with HIC-1. HIC-1 is a marker which can be used diagnostically, prognostically and therapeutically over the course of such disorders.

REFERENCES:
Makos et al. (1993) Cancer Res. 53:2715-2718, Jun.
Makos et al. (1993) Cancer Res. 53:2719-2722, Jun.
Makos et al. (1992) Proc. Natl. Acad. Sci USA 89: 1929-33, Mar.

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