Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2006-10-03
2006-10-03
Helms, Larry R. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S388850, C530S391300, C530S391700, C424S130100, C424S133100, C424S156100, C424S178100, C424S183100
Reexamination Certificate
active
07115716
ABSTRACT:
The invention provides tumor-specific human monoclonal antibodies and functional fragments. Also provided are nucleic acids encoding tumor-specific human monoclonal antibodies and functional fragments. A method for reducing neoplastic cell proliferation is also provided. The method consists of administering an effective amount of a tumor-specific human monoclonal antibody or functional fragment. Also provided is a method of detecting a neoplastic cell in a sample. The method consists of contacting a cell with a tumor-specific monoclonal antibody or functional fragment and detecting the specific binding of the human monoclonal antibody or functional fragment to the sample.
REFERENCES:
patent: 6787638 (2004-09-01), Watkins et al.
Rudikoff et al. Proc. Natl. Acad. Sci. USA (1982) vol. 79. p. 1979.
Pancook et al (Hybridoma and Hybridomics, 20, Nov. 6, 2001 pp. 383-396).
Eli Lilly and Company
Geppert Caren D.
Helms Larry R.
Tungaturthi Parithosh K.
Wiskerchen MaryAnn
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