Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1985-01-31
1989-05-09
Moskowitz, Margaret
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
4351722, 4352401, 43524027, 530387, 424 11, 424 859, 424 93, 436548, 436813, 935 93, 935 96, 935100, 935104, 935107, C12P 2100, C12N 500, C12N 1500, C07K 1500
Patent
active
048289914
ABSTRACT:
Monoclonal antibodies produced by hybridoma or transformed B-cell lines deriveed from B-cells of cancer patients actively immunized with autologous tumor antigen. These monoclonal antibodies can be used in both diagnostic procedures and therapy for human cancers.
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Schlom, J. et al., Proc. Natl. Acad. Sci, U.S.A., 77 (11): 6841-6845 (11-1980).
Stedman's Medical Dictionary, 24th ed., Williams & Wilkins, Baltimore (1982), p. 144.
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Ibid, pp. 163-170, M. C. Glassy et al.
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Ibid, pp. 181-184, P. N. W. Edwards et al.
Kohler and Milstein, Nature, vol. 256 (1975), p. 495.
L. Olsson and H. S. Kaplan, "Human-human hybridomas producing monoclonal antibodies of predefined antigenic specificity," Proc. Natl. Acad. Sci., vol. 77 (Sep. 1980) pp. 5429-5431.
Hanna, Jr. Michael
Haspel Martin V.
Hoover, Jr. Herbert C.
Akzo N.V.
Blackstone William M.
Moskowitz Margaret
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