Tumor rejection antigens which correspond to amino acid sequence

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 435 723, 424 9371, 4242771, 530324, 530325, 530326, 530327, 530328, 530329, 530330, C01N 3353, C01N 33574, C07K 706, C07K 708, C07K 1482

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active

056838867

ABSTRACT:
A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as BAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as BAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigen precursor molecules are described.

REFERENCES:
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Van der Bruggen, et al., "A Gene Encoding An Antigen Recognized By Cytolytic T Lymphocytes On a Human Melanoma", Science 254: 1643-1647 (Dec. 1991).
Brasseur, et al., "Human Gene MAGE-1, which codes for a tumor rejection antigen, is expressed by some breast tumors", Int. J. Cancer 52: 839-841 (1992).
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