Tumor rejection antigens presented by HLA-B44 molecules, and use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 435 721, 435 723, 530328, 436 64, G01N 33574, C07K 706

Patent

active

060602570

ABSTRACT:
Tumor rejection antigens presented by HLA-244 molecules are described. These peptides are useful in diagnostic and therapeutic methodologies. The tumor rejection antigens are derived from MAGE tumor rejection antigen precursors.

REFERENCES:
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Khanna et al., "Localization of Epstein-Barr Virus Cytotoxic-T Cell Epitopes Using Recombinant Vaccinia: Implications for Vaccine Development", J. Exp. Med. 176: 169-176 (Jul. 1992).
Parker et al. J. Immunol. 149:3580-3587, Dec. 1992.
Englehard, V.H. Current Opinion in Immunol. 6:13-23, 1994.
Salgaller et al. Cancer Immunol. Immunother. 39(2):105-16 (see abstract), 1994.
Kumar et al. PNAS 87:1337-41, Feb. 1990.

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