Tumor rejection antigen precursors, tumor rejection antigens and

Details Tumor rejection antigen precursors, tumor rejection antigens and Tumor rejection antigen precursors, tumor rejection antigens and

1994-05-02

1999-07-20

Cunningham, Thomas M.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

4241851, 514 15, 530395, 530806, 530828, C07K 706, A61K 3808

Patent

active

059257296

ABSTRACT:
The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which is recognized by cytotoxic T cells, leading to lysis of the tumor which expresses it. Also described are cells transfected by the DNA sequence, and various therapeutic and diagnostic uses arising out of the properties of the DNA and the antigen for which it codes.

REFERENCES:
patent: 5342774 (1994-08-01), Boon et al.
patent: 5405940 (1995-04-01), Boon et al.
patent: 5462871 (1995-10-01), Boon-Falleur et al.

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